1 Introduction Autologous fat grafting, or lipofilling, is a widely used technique in reconstructive and aesthetic surgery for volume augmentation, soft tissue regeneration, and rejuvenation (Abu-Ghname et al., 2019). However, despite its popularity, a key limitation of this technique lies in the unpredictable resorption of the transplanted fat, with volume loss ranging from 20% to 90% (Shauly et al., 2022; Debuc et al., 2023; Khouri et al., 2014; Doornaert et al., 2019).
