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Articles by J. A. Wesson
Predicting brain amyloid load with digital and blood-based biomarkers - Alzheimer's Research & Therapy
In this study, a total 349 participants were recruited from Guangzhou health aging and dementia cohort from March 2020 to March 2024, including participants with or without cognitive impairment. All participants underwent detailed cognitive assessment including MMSE, MoCA, Clinical Dementia Rating (CDR), Functional Activities Questionnaire (FAQ), MemTrax, blood tests, and neuroimaging including MRI, PET/CT (Florbetapir and Fludeoxyglucose ).
Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test - BMC Women's Health
Materials and methods Participants were enrolled continuously between September 2019 and April 2021. All participants were recruited through in-person discussion with patients who volunteered to participate in the study on the in-patient ward before their first chemotherapy session in the First Affiliated Hospital of Kunming Medical University.
The Role of the Brainstem in Sleep Disturbances and Chronic Pain of Gulf War and Iraq/Afghanistan Veterans
Yu Zhang1* Matthew Moore1, 2 Jennifer S. Jennings1 J. David Clark1, 3 Peter J. Bayley1, 2 J. Wesson Wesson Ashford1, 2 Ansgar J.
Using MemTrax memory test to screen for post-stroke cognitive impairment after ischemic stroke: a cross-sectional study
Introduction According to the latest report by Global Burden of Diseases (GBD) 2019 Stroke Collaborators, stroke is still one of the two most common causes of death and the third most common cause of death and disability combined (Feigin et al., 2021). The most challenging long-term sequelae affecting stroke survivors include physical, emotional, and cognitive impairments (Intercollegiate Stroke Working Party, 2012).
Advancing screening for cognitive impairment: the memtrax continuous recognition test
Extensive efforts to find a treatment for Alzheimer’s disease (AD) span over 40 years, with the often-repeated request for better means to assess the principal dysfunction of this disease, memory impairment [1, 2]. Tremendous costs and resources have already been consumed in the development of treatments for this prevalent and well recognized condition, e.g., over $40 billion [3].
Putative Survival Advantages in Young Apolipoprotein ɛ4 Carriers are Associated with Increased Neural Stress
METHOD FOR GRADING QUALITY OF EVIDENCE As noted previously, the literature on associations between ɛ4 status in otherwise healthy young subjects can be subdivided into several categories including: cardiovascular responses (Table 1); reproduction and development (Table 2); co-morbidities (Table 3); resistance to infectious disease (Table 4); responses to head injury (Table 5); biochemical differences possibly related to neural stress (Table 6); brain structure-function (Table 7); and mental...
Osteopontin-a molecule for all seasons
Introduction Osteopontin (OPN) is a multifunctional protein, and although highly expressed in bone, it is also expressed by various cell types including macrophages, endothelial cells, smooth muscle cells and epithelial cells.1,,2 OPN is involved in diverse biological processes and the aim of this review is to give a broad outline of some important aspects of the biology of OPN.
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