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This is an unedited manuscript that has been accepted for publication. NPG are providing this early version of the manuscript as a service to our customers. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers apply.
To confirm their role in oncogenesis and gain insight into the mechanism whereby these novel fusions promote disease, we introduced each of them as well as their individual gene counterparts into murine hematopoietic progenitor cells that were assessed in murine syngeneic transplantation models. Accompanying histological, immunophenotypic and genome-wide molecular characterization of resultant tumors delineated common and unique modes of leukemogenesis.
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