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Background Tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonist, shows a remarkable ability to lower blood glucose, enabling many patients with long-standing type 2 diabetes to achieve normoglycaemia. We aimed to understand the physiological mechanisms underlying the action of tirzepatide in type 2 diabetes. Methods This multicentre, randomised, double-blind, parallel-arm, phase 1 study was done at two centres in Germany.
The full text of this article hosted at iucr.org is unavailable due to technical difficulties. ORIGINAL ARTICLE Lower rates of hypoglycaemia in older people with type 2 diabetes when using insulin degludec versus insulin glargine U100: results from SWITCH 2 Simon R Heller Corresponding Author E-mail address: s.heller@sheffield.ac.uk https://orcid.org/0000-0002-2425-9565 University of Sheffield, Sheffield, UK Correspondence Prof.
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