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Articles by J. Hoffmann
An assessment of changes in the abundance of two Australian Acacia species under biological control in the Southwestern Cape region, South Africa
ABSTRACT Considerable investments have been made in the biological control of invasive Australian Acacia species in the Fynbos biome of South Africa. The biological control agents introduced for the most invasive Acacia species do not kill standing trees but rather reduce the reproductive output, thereby reducing the rate of spread. Here, we consider the changes in the abundance of Acacia saligna (Labill.) H. L. Wendl. and Acacia cyclops A. Cunn. ex G.
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Early start to volatile cycling - Nature Geoscience
Ancient metamorphosed basalts show a sulfur isotopic fingerprint of surface sediment, suggesting volatile cycling by a subduction-like process was occurring more than 3.8 billion years ago.
Abstract No. 103 Changes in the Match: Results of an IR Applicant and Program Director Survey Regarding Virtual Interviews and Step 1 Pass/Fail
Abstract No. 102 Using Representation Quotients to Examine Trends in Representation of Racial/Ethnic and Gender Groups Applying and Matriculating into Interventional Radiology Residency Programs Between 2017 and 2021
Abstract No. 615 The emerging IR residency: consecutive 2-year medical student IR integrated match survey results from 2017 and 2018
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. To elucidate factors utilized by medical students that determine their program application preferences, match rank list as well as to evaluate their interview and match experiences in order to identify key elements that interventional radiology (IR) program directors may use to improve and optimize the Integrated IR Match.
Differences in immune infiltrates in SCC under immunosuppression
Organ transplant recipients (OTR) who require the long‐term use of immunosuppressant medications to prevent organ rejection are more than 65 times more likely than the general population to develop squamous cell carcinoma of the skin (SCC), which is a type of skin cancer and the most frequent malignant tumor after organ transplantation. Allegedly, the immune system in the skin may influence the disease as SCCs tend to behave more aggressively in immunosuppressed patients.
Altered density, composition and microanatomical distribution of infiltrating immune cells in cutaneous squamous cell carcinoma of organ transplant recipients
The inflammatory tumor microenvironment is crucial for effective tumor control and long-term immunosuppression has been identified as a major risk factor for skin carcinogenesis. In solid organ transplant recipients (OTR) undergoing long-term pharmacologic immunosuppression an increased incidence of cutaneous squamous cell carcinoma (SCC) and more aggressive tumor growth compared to immunocompetent patients (IC) has been reported.
Dimethyl fumarate modulates neutrophil extracellular trap formation in a glutathione and superoxide-dependent manner
Neutrophil (polymorphonuclear) granulocytes (PMN) were shown to contribute to the pathogenesis of psoriasis by releasing IL-17 and LL-37/ DNA complexes via neutrophil extracellular traps (NET), webs of chromatin strands decorated with antimicrobial peptides, in psoriatic skin. Fumaderm ® , a fumaric acid ester (FAE) formulation consisting of different FAE salts has been successfully used to treat psoriasis for decades.
Long persistence of TNF-α antagonist induced autoantibodies under subsequent treatment with Ustekinumab but no adverse effects: a case study of 14 psoriasis patients - Hoffmann - 2017 - British Journal of Dermatology - Wiley Online Library
Induction of antinuclear antibodies (ANA) is a well-documented side effect of treatment with the TNF-? antagonists Infliximab, Adalimumab, and Etanercept. In this context, occasional organ-specific and systemic autoimmune phenomena, and an association of autoantibodies with treatment response and anti-drug antibody formation were reported. In genuine autoimmune disease, the detection of autoantibodies can predate clinical manifestations by almost 6 years.
Evaluation of transmit efficiency and SAR for a tight fit transceiver human head phased array at 9.4 T
Ultra-high field (UHF, ?7 T) tight fit transceiver phased arrays improve transmit (Tx) efficiency (B +/?P) in comparison with Tx-only arrays, which are usually larger to fit receive (Rx)-only arrays inside. One of the major problems limiting applications of tight fit arrays at UHFs is the anticipated increase of local tissue heating, which is commonly evaluated by the local specific absorption rate (SAR).
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