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Discussion Our results reproduce the previously noted association between reduced FVC and lower cognitive ability in childhood. This was evident in the cross-sectional analysis at age 8, with an attenuated association persisting at age 15. Adjustment for hypothesised confounders resulted in a reduction of the estimated magnitude of the association of FVC with FSIQ at both 8 and 15 years of age, but there remained strong evidence for an association at both ages.
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