Skip To Main Content
Jacob Helm on Muck Rack

Jacob Helm

As seen in: Science Magazine
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile
Back to Jacob Helm’s profile

Articles by Jacob Helm

Graft-versus-host disease prophylaxis shapes T cell biology and immune reconstitution after hematopoietic cell transplant

|
By Maximiliano Arce, Sofya A. Osharovich, Susan DeWolf, Steven Siegel, Joseph Schmalz, Wael Saber, Alexandre Albanese, Jiayi Dong, Michael Martens, Brent R. Logan, Lorenzo Iovino, Edward Chen, James Kaminski, Donna S. Neuberg, Kyle M. Hebert, Paula Keskula, Lea Steinberg, Lorenzo Cagnin, Vanessa Hernandez, Jacob Helm, Kayleigh Ingersoll-Ohmdahl, Nicholas Winn, Jillian Zavistaski, Isabella Schichter, Zoe Katsamakis
| Science Magazine Verified
Reference #1 Abstract Supplementary Materials REFERENCES AND NOTES eLetters (0) Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract Successful hematopoietic cell transplant requires immunosuppression to prevent graft-versus-host disease (GVHD), a lethal, T cell–mediated complication.
Open in Who Shared Issue with article?

Erratum for the Research Article “Systematic analysis of cellular cross-talk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer’s disease”

|
By Maximiliano Arce, Jacob Helm, Sofya A. Osharovich
| Science Magazine Verified
Reference #1 eLetters (0) Information & Authors Metrics & Citations View Options References Figures Tables Media Share This article has 0 eLetter . In Fig. 3E of the Research Article “Systematic analysis of cellular cross-talk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer’s disease” by R. D’Oliveira Albanus et al., nine values of the “All AD (distal)” group were duplicated because of a copy-paste error (n = 360 after removal).
Open in Who Shared Issue with article?

A 5 + 1 polyene scaffold that selectively recognizes ergosterol’s conjugated diene uncouples antifungal potency from host toxicity

|
By Maximiliano Arce, Jacob Helm, Sofya A. Osharovich, Wei Liu, Qisen Deng, Feng Tang, Wenbo Zhu, Han Zhang, Tao Chen, wen xiao, Wenyan He, Nan Liu, Zongqiang Wang
| Science Magazine Verified
Reference #1 Abstract Supplementary Materials REFERENCES AND NOTES eLetters (0) Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract Amphotericin B remains the gold-standard therapy for invasive fungal infections, but its clinical utility is limited by toxicity arising from poor selectivity for fungal ergosterol over mammalian cholesterol, a challenge that decades of medicinal chemistry have failed to fully overcome.
Open in Who Shared Issue with article?

Single-nucleotide polymorphism–directed design of allele-specific antisense oligonucleotides for spinocerebellar ataxia type 3

|
By Jacob Helm, Elena Buena-Atienza, Linus Wiora, Melanie Kraft, Jakob Admard, Jeannette Hubener-Schmid, Thomas Klockgether, Matthis Synofzik, Luís de Almeida, Mafalda Raposo, Paola Giunti, Magda M. Santana, Jennifer Faber, Holger Hengel, Nicolas Casadei, Ludger Schöls, Stefan Häuser, Clemens M. Sauter, Yvonne Schelling
| Science Magazine Verified
Reference #1 Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES AND NOTES eLetters (0) Information & Authors Metrics & Citations View Options References Figures Tables Media Share This article has 0 eLetter . Abstract Spinocerebellar ataxia type 3 (SCA3), also called Machado-Joseph disease, the most common form of autosomal dominant cerebellar ataxia, is caused by a CAG repeat expansion in ATXN3.
Open in Who Shared Issue with article?
Show More