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Faculty, Staff and Student Publications Publication Date 10-1-2024 Journal Journal of Trauma and Acute Care Surgery DOI 10.1097/TA.0000000000004325 PubMedCentral® Posted Date 10-1-2025 PubMedCentral® Full Text Version Author MSS Abstract Background: Non-narcotic intravenous medications may be a beneficial adjunct to oral multimodal pain regimens (MMPRs) which reduce but do not eliminate opioid exposure and prescribing after trauma.
BACKGROUND: Evidence for effective pain management and opioid minimization of intravenous ketamine in elective surgery has been extrapolated to acutely injured patients, despite limited supporting evidence in this population. This trial seeks to determine the effectiveness of the addition of sub-dissociative ketamine to a pill-based, opioid-minimizing multi-modal pain regimen (MMPR) for post traumatic pain.
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