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Communication PDF ShareShare Abstract Not too demanding: A robust and purification‐free, one‐step synthesis has been developed to enable the on‐demand preparation of structurally diverse fluorophosphonates from a stable, and storable “toolbox” of readily accessible p‐nitrophenylphosphonates. Additionally, a reaction‐to‐assay protocol is highlighted that further facilitates the rapid screening of these valuable activity‐based probes.
Communication Dr. S. Denise Field Corresponding Author E-mail address: denise.field@pfizer.com Pfizer Worldwide Research and Development, 1 Portland St, Cambridge, MA, 02139 USA These authors contributed equally to this work. Search for more papers by this author Abstract One and only one : The degradation susceptibility of serine hydrolases was assessed by using a probe that contained a fluorophosphonate warhead and a cereblon‐binding pomalidomide.
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