Jason Pugh
United Kingdom
Covers:
Peptides, longevity, senolytics, GLP-1 receptor agonists, nootropics and biohacking. Evidence-led coverage of supplement quality, contamination and what the human trials actually show.
Doesn't Cover:
No product launches, testimonials or influencer stories. No general fitness, diet or nutrition. Nothing without published human data.
🧬 Biohacking | Longevity | Peptides
Science-backed protocols for human optimisation 🔬
Evidence, not hype. Not medical advice.
humanupgradeai.com
Jason Pugh’s Journalist Portfolio
View as a gridSpermidine and Autophagy: Strong in Mice, Null in Humans
humanupgradeai.com
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Spermidine extends lifespan in yeast, flies and mice. The SmartAge human trial found no cognitive benefit. What that gap means in practice.
Peptide Longevity Statistics 2026: Trials, Market & Data
humanupgradeai.com
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Peptide longevity statistics 2026 reveal 1,872 clinical trials, $48.9 bn market size and 412% GLP-1 growth. Latest registry data, safety updates and real-world usage trends.
FDA Peptide Reclassification 2026: UK & EU Guide
humanupgradeai.com
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The FDA Peptide Reclassification 2026 ends US compounding of 40+ peptides. This guide explains UK & EU legal options, MHRA pathways, testing requirements and safe alternatives for biohackers.
Peptide Contamination Risks & Quality Testing Guide 2026
humanupgradeai.com
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Learn the real peptide contamination risks affecting 15–40% of batches. Discover how UK researchers use independent quality testing, COAs and lab verification to stay safe.
Retatrutide vs Tirzepatide: The Comparative Evidence
humanupgradeai.com
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Phase 2 trials and network meta-analyses put retatrutide ahead of tirzepatide on mean weight loss. No head-to-head trial has compared them.
GHK-Cu Peptide Reverses Skin Ageing 20-30% in Trials
humanupgradeai.com
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Discover how GHK-Cu peptide reverses skin ageing 20-30% in human trials, boosts collagen 50-70%, accelerates wounds 2-3x. Dosages, safety, synergies for anti-ageing.
Whole-Body Cryotherapy and Inflammation: The Evidence
humanupgradeai.com
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Cryotherapy reliably lowers perceived soreness. IL-6 and CRP fall modestly at 24-48 hours, and strength recovery improves less consistently.
Partial Cellular Reprogramming: UK Biohacking Evidence
humanupgradeai.com
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Learn about partial cellular reprogramming using OSKM factors and its benefits for healthy ageing in this evidence-led UK biohacking article.