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1 INTRODUCTION Primary ciliary dyskinesia (PCD) is a rare genetic disease, occurring between 1 in every 7000–10,000 live births in most communities, characterized by defects in the motile cilia lining the respiratory tract and other organs.1 In PCD, cilial ultrastructural deficiencies lead to poorly motile cilia, which, in turn, result in reduced mucous clearance in the lungs and upper airways.
Highlights • There is a current lack of consensus regarding the radiological criteria for defining bronchiectasis in children using low-dose CT • A broncho-arterial ratio of >0.9 in children is likely abnormal and, in the appropriate clinical setting, indicates a diagnosis of bronchiectasis • Computer software enabling automated measurement of broncho-arterial ratio will facilitate establishment of age-adjusted cut-offs which will further improve diagnostic precision in paediatric...
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