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Abstract Background: Endoscopic ultrasound-guided tissue acquisition (EUS-TA) is central to the pathological diagnosis of solid pancreatic masses, but the comparative value of rapid on-site cytologic evaluation (ROSE), macroscopic on-site evaluation (MOSE), and no on-site evaluation (NONE) may vary by needle type and remains uncertain. Methods: We performed a PRISMA-DTA systematic review registered in PROSPERO (CRD420251241446).
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