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Articles by Jipeng Ding
TRPML1 inhibitor ML-SI1 suppresses prostate cancer through dual regulation of androgen receptor and polyamine metabolism
Abstract Background: Prostate cancer (PCa) is the second leading cause of cancer-related death in men worldwide, with metastasis and drug resistance representing major drivers of mortality. Transient receptor potential mucolipin 1 (TRPML1), a member of the transient receptor potential channel superfamily, is associated with several malignancies; however, its role in PCa remains unclear.
Molecular Engineering of Pure Superoxide Radical Photogenerator for Hypoxia‐Tolerant Tumor Theranostics
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202405164-sup-0001-SuppMat.docx11.5 MB Supporting Information References 1, , , , , , , , , , , , , , , , , CA Cancer J. Clin. 2011, 61, 250. 2, , , , , , , , , Small 2022, 18, 2203825. 3, , , , , Chem. Soc. Rev. 2021, 50, 4185. 4, , , , , , ACS Appl. Mater. Interfaces. 2023, 15, 36013. 5, , , , , , , , Small 2024, 2400654. https://doi.org/10.1002/smll.202400654. 6, , , , , , , , , , Photochem.
Establishing a Proteomics-Based Signature of AKR1C3-Related Genes for Predicting the Prognosis of Prostate Cancer
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Xiaoli Cui , Changcheng Li , Jipeng Ding , Zhou Yao , Tianyu Zhao , Jiahui Guo , Yaru Wang and Jing Li * Department of Pharmacology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China * Author to whom correspondence should be addressed. Int. J. Mol. Sci.
Aggregation-induced emission nanofiber as dual sensor for aromatic amine and acid vapor
Two cyano-substituted vinylacridine derivatives linked with N-dodecyl-L-phenylalaninamide through succinyl (PC2VA) and glutaryl (PC3VA) groups were synthesized and were found to exhibit aggregation-induced emission properties. These two compounds could form gels in some solvents at low concentrations and exhibit fluorescence enhancement during gelation.
Rapid gel-to-sol transition triggered by a photoacid generator under low-power light
A photoacid generator as a trigger was introduced into an acid-responsive fluorescent organogel to realize rapid gel-to-sol transition under a low powder light stimulus. The pristine yellow organogel emitted a strong blue-green fluorescence and transformed into a brown solution with emission quenching after irradiation for 20 s by 365 nm light with a light intensity of 0.1 mW/cm2. The yellow gel could be recovered with the addition of triethylamine. Such process could be repeated a few times.
Recent progress in mechanochromism of phosphorescent organic molecules and metal complexes
Organic and organometallic molecules, which change their luminescent properties through mechanical stimulus, such as emission wavelength and quantum yield, are called as mechanochromic or piezochromic materials. These functional molecules may be used as smart materials in the field of luminescent switches, mechanosensors, security papers, data storage, biological and healthcare applications. These materials are classified into two types, fluorescent and phosphorescent molecules.
Mechanical force-induced luminescent enhancement and chromism of a nonplanar D-A phenothiazine derivative
Nonplanar D-A phenothiazine derivative (PBA), in which phenothiazine and formylphenyl groups act as donor and acceptor, respectively, was designed and synthesized. The PBA emitted weak fluorescence in the solution, and its crystals had weak blue green emission with luminescent efficiency of 7.5% under UV light irradiation because of the lowest singlet (S1) of n-π* and the presence of intersystem crossing from S1 to T1.
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