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Abstract Picobirnaviruses (PBVs) are commonly detected RNA viruses in human and animal guts and are associated with multiple human diseases. Although PBVs have been assumed to infect vertebrate hosts, there is neither direct evidence for this nor any culture system to propagate PBVs. Here we demonstrate that a PBV infects bacteria and is therefore an RNA phage.
Please be advised this article contains details of domestic and family violence which may be triggering for some readers. “Coercive control” has become a buzzword in discussions around domestic violence in recent years.
Campylobacter jejuni is among the most common causes of diarrheal disease worldwide and efforts to develop protective measures against the pathogen are ongoing. One of the few defined virulence factors targeted for vaccine development is the capsule polysaccharide (CPS). We have developed a capsule conjugate vaccine against a prototype CPS, type HS23/36, that confers 100% protection against diarrhea caused by a homologous strain of C.
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