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Abstract Circular RNA (circRNA) is an emerging vaccine modality that is proposed to improve stability, reduce reactogenicity and extend antigen expression compared with linear mRNA. However, the relative contributions to vaccine performance of its covalently closed structure, its preparation quality and nucleotide modifications remain poorly described. Here, we systematically dissected these parameters in vivo across two antigen systems.
UNC student uses his past to launch an empathetic leadership program Joanna Kuang | Published 6 minutes ago Just seven years ago, junior Amit Dodani was a timid eighth-grader, insecure about his speech impediment. The inability to speak in public became one of his greatest fears. Today, Dodani is a confident speaker, one who uses his past to inspire young students to become empathetic leaders.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
