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Abstract Fragile X Syndrome (FXS) is a neurodevelopmental disorder characterized by intellectual disability and difficulties in social interaction. This last feature is reproduced in the Fmr1 KO mouse, an animal model of FXS. In mice, the accessory olfactory bulb (AOB) is the first central region of the vomeronasal system implicated in the processing of chemical cues that trigger social and sexual behaviors.
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