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Articles by John Pauling
The association of outdoor temperature and self-reported Raynaud's phenomenon severity among people with systemic sclerosis: a Scleroderma Patient-centered Intervention Network Cohort study
aLady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada bDepartment of Psychiatry, McGill University, Montreal, QC, Canada cDepartment of Medicine, McGill University, Montreal, QC, Canada dDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada eBiomedical Ethics Unit, McGill University, Montreal, QC, Canada fDepartment of Psychology, McGill University, Montreal, QC, Canada gDepartment of Clinical...
Changes in the incidence and prevalence of systemic lupus erythematosus between 1990 and 2020: an observational study using the Clinical Practice Research Datalink (CPRD)
Discussion Between 1991 and 2019, we observed an overall incidence rate of 5.47 cases per 100 000 patient-years. The most common age group for incident SLE was 40–54. There was a higher incidence and prevalence of SLE in women than men. UK prevalence of SLE, for men and women, has increased over time. We observed a higher overall incidence rate than that of Rees et al in the last CPRD study reporting trends in UK SLE epidemiology.6 Methodological differences between studies may account for this.
Pharmacological management of systemic sclerosis associated interstitial lung disease
Abstract Introduction Interstitial lung disease (ILD) is a major cause of disease related morbidity and one of the leading causes of mortality in patients with systemic sclerosis (SSc). Many patients will be diagnosed with SSc before the emergence of clinically meaningful ILD. Screening and early recognition of SSc-ILD allows prompt intervention and improved clinical outcomes.
Factors influencing patient decision‐making concerning treatment escalation in Raynaud’s phenomenon secondary to systemic sclerosis
ORIGINAL ARTICLE Michael Hughes, Corresponding Author Michael.hughes-6@postgrad.manchester.ac.uk orcid.org/0000-0003-3361-4909 Department of Rheumatology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK Corresponding author Dr Michael Hughes BSc (Hons) MSc MBBS MRCP (UK) (Rheumatology) PhD, Consultant Rheumatologist, Department of Rheumatology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Clinical Images: Lindsay’s nails in early limited cutaneous systemic sclerosis with severe digital vasculopathy
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Fulminant immune-mediated necrotising myopathy (IMNM) mimicking myocardial infarction with non-obstructive coronary arteries (MINOCA)
Unusual presentation of more common disease/injury Fulminant immune-mediated necrotising myopathy (IMNM) mimicking myocardial infarction with non-obstructive coronary arteries (MINOCA) http://orcid.org/0000-0001-9424-0854Sophie Glenn-Cox1, Robert William Foley1, John D Pauling2,3 and Jonathan C L Rodrigues1 1Radiology Department, Royal United Hospital Bath NHS Trust, Bath, UK 2Rheumatology Department, Royal National Hospital For Rheumatic Diseases, Bath, UK 3Department of Pharmacy and...
Multidisciplinary collaboration among young specialists: results of an international survey by the emerging EULAR network and other young organisations
Multidisciplinary collaboration among young specialists: results of an international survey by the emerging EULAR network and other young organisations http://orcid.org/0000-0002-6008-503XAurélie Najm1, Marie Kostine2,3, John D Pauling4,5, Ana Carina Ferreira6,7, Kate Stevens8, Evelyn Smith9, Ibon Eguiluz-Gracia10, http://orcid.org/0000-0002-8895-6941Paul Studenic11, http://orcid.org/0000-0002-0011-5102Javier Rodríguez-Carrio12, Sofia Ramiro13,14, http://orcid.org/0000-0003-1105-5640Alessia...
The promise, perceptions, and pitfalls of immunoassays for autoantibody testing in myositis
Abstract Background A myositis-specific autoantibody can now be identified in the majority of patients with myositis. They identify homogeneous patient subgroups and are key tools in developing a personalized approach to disease management. There is substantial clinical interest in exploiting myositis autoantibodies as biomarkers, and consequently, a large number of commercial assays have been developed for their detection. These assays are already in widespread clinical use.
Raynaud phenomenon and digital ulcers in systemic sclerosis
Abstract Raynaud phenomenon is a symptom complex caused by impaired digital perfusion and can occur as a primary phenomenon or secondary to a wide range of underlying causes. Raynaud phenomenon occurs in virtually all patients with systemic sclerosis (SSc) and is often the earliest clinical manifestation to occur.
The Experience of Raynaud's Phenomenon in Systemic Sclerosis
Table 1. Existing patient- and clinician-reported outcome instruments for assessing SSc-RP Name Study Item metric Recall period (days) Score Item wording Patient-reported outcomes Raynaud's Severity Score Wigley et al.[34] 11-point NRS (0–10) 1 Mean daily score over 3-week period Patients were asked to consider in their Raynaud severity score the number and duration of attacks; symptoms, such as numbness, burning, and pain and tingling; hand disability; and influence of cold on daily activity.
Behaviour change interventions for the management of Raynaud’s phenomenon: a systematic literature review
Behaviour change interventions for the management of Raynaud’s phenomenon: a systematic literature review Jo Daniels1, John D Pauling2,3, Christopher Eccleston4,5 1 Department of Psychology, The University of Bath, Bath, UK 2 Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, UK 3 Department of Pharmacy and Pharmacology, The University of Bath, Bath, UK 4 Centre for Pain Research, University of Bath, Bath, UK 5 Department of Clinical and Health Psychology, Ghent...
Could nailfold videocapillaroscopy usher in a new era of preventative disease-modifying therapeutic intervention in systemic sclerosis?
The complementary value of nailfold videocapillaroscopy (NVC) abnormalities and autoimmune serology in predicting the progression of undifferentiated RP to SSc is widely accepted and reflected in the 2013 EULAR/ACR classification criteria for SSc [1, 2]. In this journal, Markusse et al.
NSW green lights Broken Hill water pipeline
Construction of the pipeline is part of the $500 million investment strategy to secure Broken Hill’s water supplies – representing the largest investment in regional water security in the state on record. “This is the single biggest investment to secure a town’s water supply in the history of NSW,” said NSW Premier Mike Baird. “Water security has been a constant challenge for Broken Hill since it was founded in 1883.
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