Jon Bier
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Articles by Jon Bier
Doctors Told Him He'd End Up in a Wheelchair. He Found a Cure For His Illness and Built a Company Around It.
Viome's Momo Vuyisich believes the microbiome is key to preventing disease. But the medical establishment has been slow to catch up. Key Takeaways Momo Vuyisich was running out of time. The scientist had spent years battling a mysterious auto inflammatory disease. His joint pain was getting progressively worse and doctors couldn't explain why. They told him he could end up in a wheelchair within 10 to 20 years. For Vuyisich, that prognosis was unacceptable.
Doctors Told Him He’d End Up in a Wheelchair. He Found a Cure For His Illness and Built a Company Around It.
8 hours ago For four decades, China’s rise was built on an extraordinary bargain with the world. China offered labor, scale and, eventually, an industrial ecosystem of unparalleled depth. The world supplied technology, capital and markets. China became richer. The rest of the world got cheaper and increasingly …
This founder sold his company for $1.04 billion and planned to take 2 years off. His retirement lasted 7 minutes
Lones spotted a healthcare hole in treating sleep apnea. Daybreak offers an alternative to the unpopular CPAP machine. The business model limits inventory costs and allows the company to move quickly. Here's a statistic that might keep you up at night: As many as 83 million U.S. adults suffer from obstructive sleep apnea , a condition that causes them to stop breathing over and over again while they sleep , waking up dozens or even hundreds of times a night.
This Founder Sold His Company for $1.04 Billion and Planned to Take 2 Years Off. His Retirement ‘Lasted 7 Minutes'
Wesley Lones's company Daybreak tackles sleep apnea entirely from home, replacing the CPAP mask with a custom-fit oral appliance. Lones spotted a healthcare hole in treating sleep apnea. Daybreak offers an alternative to the unpopular CPAP machine. The business model limits inventory costs and allows the company to move quickly.
He Wrote Down Everything People Hate About Going to the Doctor. Then He Built a Business to Fix It.
Dr. Darshan Shah created Next Health to take the fear and frustration out of doctor visits. Now, he has more than 25 clinics around the world. Key Takeaways When Dr. Darshan Shah, a board-certified surgeon, set out to create a different kind of medical clinic, he took out a whiteboard and made a list of everything people hate about going to the doctor. Bad parking. Old furniture. A grumpy person at the front desk. Long waits. Old magazines. Then he set about doing the opposite.
Would You Pay $249 for a Water Pitcher? These Founders Are Betting You Will.
Opinions expressed by Entrepreneur contributors are their own. A basic water filter pitcher typically costs around $20 to $40. Rorra, a startup water filtration company known for its stainless-steel countertop system, is asking $249 for its new version. That’s a lot of money for a water pitcher. So what makes founders Brian Keller and Charlie Carlisle think people will pay a premium for it? Part of their pitch is that this isn’t your typical plastic pitcher.
The $6.8 trillion wellness economy is overwhelming. This doctor says you need a 'medical chaperone' to find what actually works.
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The $6.8 Trillion Wellness Economy Is Overwhelming. This Doctor Says You Need a ‘Medical Chaperone’ to Find What Actually Works.
The $6.8 trillion wellness economy offers consumers a wide range of health-related products and services, making it challenging to determine what actually works. Dr. Jeffrey Wiegers advocates for the role of a "medical chaperone" to help individuals navigate the overwhelming array of supplements, treatments, and biohacks in the wellness industry.
She Spent 6 Months Looking for the Perfect Spring Water. What She Found Changed Her Entire Business. Original
Opinions expressed by Entrepreneur contributors are their own. When shoppers pick up a bottle of spring water decorated with snow-capped mountains and cascading waterfalls, they assume what’s inside is as pure as nature can make it. Clara Sieg did, too. So when the former venture capitalist set out to build a bottled water company, she spent six months traveling the country in search of the perfect spring. What she found surprised her. “Every source has some footnote,” she says.
How Two Friends With No Experience Built Neuro Into a $100 Million Plus Brand
Opinions expressed by Entrepreneur contributors are their own. Kent Yoshimura and Ryan Chen admit they were naive when they set out to build Neuro. Nothing in their backgrounds suggested they could pull it off. Neither had ever formulated a product, built a brand or worked in marketing. They were just two fitness-obsessed friends who started mixing their own energy supplements, then wondered why no one had put that boost into a piece of gum. “Red Bull created the energy drink category in 1987.
How Two Friends With No Experience Built Neuro Into a $100 Million Plus Brand
"I remember looking at Kent and thinking, am I doing this wrong? Should I be raising a ton of money?" he says. The answer was no. In hindsight, the lean early years were exactly what kept them motivated. "It's hard to stay hungry when you're fed," Chen says. Slowly, the bet paid off. Neuro did $109,000 in its first year, $750,000 in its second, and $1.5 million in its third, growing steadily while the better-funded darlings came and went.
He Bet on a ‘Super Fuel’ Nobody Had Heard Of. Now Ketone-IQ Is a $100 Million Company.
Opinions expressed by Entrepreneur contributors are their own. Most founders chase a trend and try to flip the company before it fades. Michael Brandt did the opposite. The Stanford computer science grad and marathoner was deep into biohacking. That led him to discovering ketones, a backup “super fuel” your body makes by turning fat into clean, steady energy. The catch is it only kicks in when you starve it, during a long fast or a hard workout.
He Bet on a ‘Super Fuel’ Nobody Had Heard Of. Now Ketone-IQ Is a $100 Million Company.
Taste was far from the biggest challenge. "It's not easy to be the first tracks in the snow," Brandt says. There was no supply chain to plug into and no customer who knew what a ketone was. His fix for the supply problem was to become the supply. The company coordinated production itself, and Brandt now claims it makes up "80% of the ketone market." To him, that's the real moat. "There's no what without the how," he says.
She Watched Doctors Give Her 92-Year-Old Grandmother ‘the Worst of the Worst’ Nutrition. Now She’s Coming for a $6 Billion Market: ‘If Not Me, Then Who?’
Opinions expressed by Entrepreneur contributors are their own. When Jess Haghani’s grandmother Lucille came home from heart surgery, the family did everything the doctors told them to. They bought the recommended food and shakes, feeding her a steady diet of ultra-processed products whose formulas hadn’t changed in decades. Haghani was stunned at what the medical system was handing an older woman in recovery. “It was just the worst of the worst nutrition out there,” she says.
She Watched Doctors Give Her 92-Year-Old Grandmother ‘the Worst of the Worst’ Nutrition. Now She’s Coming for a $6 Billion Market: ‘If Not Me, Then Who?’
Photo courtesy of Lucille Health Entrepreneur Media LLC and Yahoo Finance LLC may earn commission or revenue on some products and services through the links below. Key Takeaways Haghani never planned to be a founder until her grandmother’s post-surgery recovery exposed how bad senior nutrition had become. With no money or medical background, she built Lucille Health by assembling experts from Harvard, Erewhon and a Chicago lab.
This CEO Says Screen Addiction Is ‘the New Tobacco.’ Here’s What His Company Is Doing to Fight Back
Opinions expressed by Entrepreneur contributors are their own. Robin Thurston thinks the most dangerous product in modern life may be the screen staring right back at you. “This really is the new tobacco,” says the CEO of Outside Inc., who believes Silicon Valley has spent years engineering products designed to keep people indoors. “When you aggregate big tech into this, their primary goal is to capture our attention,” he says. Public sentiment is starting to catch up.
This CEO Says Screen Addiction Is ‘the New Tobacco.’ Here’s What His Company Is Doing to Fight Back
Outside Inc Entrepreneur Media LLC and Yahoo Finance LLC may earn commission or revenue on some products and services through the links below. Key Takeaways Tech isn’t the enemy — the same mechanics that hook people to screens can push them outdoors. Consumers are shifting from buying products to buying experiences. Partnerships, not individual brands, will define the next era of the outdoor industry.
These Founders Built a $60 Device That Solves Phone Addiction — Hundreds of Thousands of People Are Already Using It
Opinions expressed by Entrepreneur contributors are their own. The average American spends 20 years of their life staring at their phone. That’s about 5 to 6 hours a day mindlessly scrolling through apps. TJ Driver, 26, and Zach Nasgowitz, 27, had this exact problem. After graduating college, they were brainstorming business concepts, trying to come up with problems they could solve. But they noticed they’d constantly get distracted by looking at their phones. “We’d have all these ideas,” Driver says.
They Built a $50 Million Business Before GLP-1s Became Mainstream. Now They’re Eyeing This New Health Frontier Original
Opinions expressed by Entrepreneur contributors are their own. Years before “longevity” became a wellness buzzword, Josh and Katy Whalen were building Joi + Blokes, a company focused on helping patients feel better as they age. The married couple started the business after struggling with hormonal health issues in their own lives. Katy was dealing with postpartum health challenges and perimenopause, while Josh learned he had extremely low testosterone.
After Addiction and Ironman Failure, This Founder Adopted a Rule That Changed Everything
Opinions expressed by Entrepreneur contributors are their own. Most authors would take a victory lap when their book becomes a national bestseller. Not Ken Rideout. “I would have been happier if it made the New York Times list,” he says of his new memoir, Everything You Want Is On the Other Side of Hard. For Rideout, winning isn’t enough. The real test is how close you get to the standard you set for yourself, and how quickly you raise it again.
This Founder Went on Shark Tank After His Last Startup Was ‘Publicly Eviscerated’ — Now He’s on a $12 Million Run Rate
Opinions expressed by Entrepreneur contributors are their own. In October 2025, Doug Evans appeared on Shark Tank to pitch The Sprouting Company, a countertop home sprouting system that lets people grow fresh, nutrient-dense sprouts without soil or sunlight. Before the Season 17 episode aired, The Sprouting Company was doing $200,000 in monthly revenue. By December, it hit $540,000. And by March, Evans was tracking over $1 million a month, putting the company on a $12 million annual run rate.
This Married Couple Built a Cereal Brand in Their Cramped One-Bedroom Apartment — Now It’s in 15,000 Stores
Opinions expressed by Entrepreneur contributors are their own. Margaret Wishingrad remembers standing in the cereal aisle of her grocery store, reading ingredient labels. It was sugar and grains for days. She had a baby boy who just started on solid foods, and there wasn’t a single option she felt comfortable feeding him. She told her husband, Ian, who ran an ad agency building brands for other companies. Faster than you can say snap, crackle, pop, a lightning bolt struck.
This Married Couple Built a Cereal Brand in Their Cramped One-Bedroom Apartment - Now It’s in 15,000 Stores
Three Wishes Cereal Entrepreneur Media LLC and Yahoo Finance LLC may earn commission or revenue on some products and services through the links below. Margaret and Ian Wishingrad launched Three Wishes Cereal from their one-bedroom apartment in 2019 after finding zero healthy cereal options for their baby. The grain-free, high-protein brand is now sold in more than 15,000 stores after they bootstrapped it with $250,000.
He Sold His Grass-Fed Jerky Company for Millions. Then He Started One of the Hardest Businesses in Food.
Opinions expressed by Entrepreneur contributors are their own. Robby Sansom would have preferred not to start his company. Not because it was a bad idea — but because he hoped someone else would do it first. After selling Epic Provisions, the company that pioneered grass-fed jerky and made him financially set for life, he was prepared to ride off into the sunset. Then visitors started showing up at ROAM Ranch in Fredericksburg, Texas, where Sansom owns regenerative bison.
He Sold His Grass-Fed Jerky Company for Millions. Then He Started One of the Hardest Businesses in Food.
Force of Nature Entrepreneur Media LLC and Yahoo Finance LLC may earn commission or revenue on some products and services through the links below. Robby Sansom co-founded Force of Nature in 2019 after selling Epic Provisions, the company that pioneered grass-fed jerky. Force of Nature aggregates regenerative ranchers to sell healthier meat direct-to-consumer, in 5,000+ grocery stores, and to restaurants nationwide.
She Was a Broke Backpacker Surviving On Oranges — Now She Runs a Wellness Empire. Here’s How.
Opinions expressed by Entrepreneur contributors are their own. When she graduated magna cum laude from Georgetown University, she backpacked across over 50 countries around the world for three years, including India, where she discovered and studied yoga and meditation. Afterwards, she moved to a rent-controlled apartment in NYC, went back to nutrition school and became a yoga teacher. When she was getting started, there were days when lunch would be three oranges she could buy for a dollar.
Trainer Built $191M Brand Making Activewear She Couldn't Find
Opinions expressed by Entrepreneur contributors are their own. Krissy Cela was literally stitching her own workout clothes—cutting waistbands, cropping tops, dying fabric—because she couldn’t find what she needed. The problem wasn’t just one thing. No brand solved all three of her needs at once: color, performance, and silhouette. Then, there was the issue of price. Premium activewear brands like Lululemon were charging up to $128 for a pair of leggings.
This Founder Built Natural GLP-1 Alternative Before the Boom
Opinions expressed by Entrepreneur contributors are their own. Becca McCarthy says she’s always been good at recognizing when something is about to break into the mainstream. She has spent her career inside startups, helping turn early interest into real markets and building products before most people realize there’s demand for them. That’s why, a few years ago, when she started hearing people in her network talking about GLP-1 drugs, she paid attention.
How This Founder Made Dry January a Yearly Movement
Opinions expressed by Entrepreneur contributors are their own. Bill Shufelt loved beer. He loved sports bars, restaurants, and the ritual of cracking open a cold one with friends. But he didn’t love the way beer made him feel. The alcohol was having negative effects on his health and his productivity. Shufelt stopped drinking in 2013, but he was frustrated by the lack of great-tasting non-alcoholic beer options available to him at the time.
This Is How Athletic Brewing Became America's Top NA Beer
Opinions expressed by Entrepreneur contributors are their own. Bill Shufelt loved beer. He loved sports bars, restaurants, and the ritual of cracking open a cold one with friends. But he didn’t love the way beer made him feel. The alcohol was having negative effects on his health and his productivity. So in 2018, Shufelt set out to solve a problem that had plagued the beer industry for years: how to make a non-alcoholic variety that people would actually be proud to drink.
Ex-CIA Officer Turned Spycraft Into Rucking Movement
Opinions expressed by Entrepreneur contributors are their own. Emily McCarthy spent years working overseas as a CIA case officer. While she was stationed in West Africa, her husband, Jason McCarthy, a former U.S. Army Special Forces officer, came to visit. He’d done tours in Afghanistan and Iraq carrying heavy rucksacks through hostile terrain, so the environment immediately caught his attention. He told her she needed a rucksack and pulled out one of his military-issued packs.
The $160K Recovery Chamber Pro Athletes Swear By
Opinions expressed by Entrepreneur contributors are their own. Getting people to try something new is hard. Getting skeptics to lie down inside a $160,000 device is harder. Brian Le Gette learned that early while demonstrating his recovery chamber to an NHL player who didn’t want to be there. “His wife made him do it,” Le Gette recalls. The player climbed in reluctantly, expecting little. When the session ended, he didn’t come out. After several minutes, Le Gette and a colleague checked in.
How Dermatologist Brothers Fixed Hair Loss Treatment
Opinions expressed by Entrepreneur contributors are their own. After decades of treating hair loss, board-certified dermatologist brothers Ben and Sean Behnam began to notice a familiar pattern. Patients arrived frustrated, having cycled through shampoos and medications that promised results but rarely delivered a fuller head of hair. They realized hair loss was being treated less like a medical condition and more like a guessing game.
This CEO Wants to Remove the 'Number One Barrier' to Addiction Recovery
Opinions expressed by Entrepreneur contributors are their own. The way John Driscoll sees it, when people have trouble with their vision, they go to the eye doctor. They don’t wait to hit rock bottom. They don’t try to “tough it out.” They put on glasses. Problem solved. No secrecy or confusion about whether eyesight is a moral issue. So why doesn’t the same logic apply to addiction? Driscoll has spent his career wrestling with that question.
This CEO wants to remove the 'number one barrier' to addiction recovery
The way John Driscoll sees it, when people have trouble with their vision, they go to the eye doctor. They don't wait to hit rock bottom. They don't try to "tough it out." They put on glasses. Problem solved. No secrecy or confusion about whether eyesight is a moral issue.So why doesn't the same logic apply to addiction?Driscoll has spent his career wrestling with that question. As the president and CEO of Caron Treatment Centers, he believes the answer is maddeningly simple.
Watch Out for This Major Red Flag When You’re Starting a Business, Says a Serial Investor
Investors call out scattered and unfocused pitches. Perell offers a solid piece of advice for any entrepreneur. Season 13 of Entrepreneur Elevator Pitch is back with one of its most explosive episodes yet — and this ride to the top floor is packed with big personalities, bigger numbers and real-time drama you do not want to miss. With just 60 seconds to pitch their business, founders step into the elevator and put everything on the line.
How This Water Filtration System Became An 8-Figure Business
Opinions expressed by Entrepreneur contributors are their own. When his young daughter’s eczema worsened, Brian Keller tried everything modern parenting prescribes. Nothing worked. Desperate, he replaced the ordinary showerhead in their bathroom with a filtered one. Within a couple of days, his daughter had perfectly clear skin. The speed of the change forced him to go online searching for a reliable filtration system. But what he found surprised him.
Wellness Goes IRL at the Eudēmonia Summit
Opinions expressed by Entrepreneur contributors are their own. In a culture obsessed with algorithms, two entrepreneurs are betting that true success isn’t measured by clicks or views but by in-real-life community gatherings. That’s the driving idea behind the Eudēmonia Summit, a four-day health and wellness event in West Palm Beach, Florida from November 13-16.
In the Controversial World of Nicotine, One Brand Is Betting Less Is More
Opinions expressed by Entrepreneur contributors are their own. Most brands are marketed to sell as many units as possible. But Athletic Nicotine comes with a different playbook. Use less, benefit more. The company makes low-dose, slow-release nicotine pouches designed to sharpen focus without the smoke or tobacco. Each pouch contains 1.5 milligrams of synthetic, pharmaceutical-grade nicotine. The result is a subtle lift rather than a jolt, a way to stay locked in without overstimulation.
How He Built a $230 Million Sports Nutrition Brand Without Ads
Opinions expressed by Entrepreneur contributors are their own. RAW Nutrition happened by accident. In 2019, Dom Iacovone and his partner, Matt Jansen, were running Revive MD, a small vitamin company built on ingredient transparency. When fans of his product kept asking for pre-workouts and protein powders, Iacovone had to decide whether to stay in the vitamin lane or cross over into the cutthroat sports nutrition space. “If we were going to do it, we were going to do it right,” he says.
Pat Tenore Returns With TENŌRE, a Brand Rooted in Community
Opinions expressed by Entrepreneur contributors are their own. Pat Tenore has always put community ahead of profitability. When he sponsored local gyms in Hawaii, it was about bringing people together in a state where “scrapping” (slang for fighting) was part of the culture. “There was a lot of tension in the North Shore,” he recalls. “You had outsiders coming in, locals feeling disrespected, and people getting into fights. I thought, what if we can help change that energy?
Dry Skin Sparked This Eight-Figure Men's Skincare Brand
When Jared Pobre and his wife, former WWE star Stacy Keibler, moved to Jackson Hole, Wyoming, he expected more time outdoors, skiing, hiking, fly-fishing. What he experienced was how extreme conditions accelerate skin aging and damage, leaving his skin raw and red. When searching for solutions for his skincare, not only were options limited, but nothing seemed to help. Out of frustration, he tried one of Keibler's pricey serums. "Within a week it cleared everything up," he says.
This Entrepreneur Turned a Dry Skin Problem Into an Eight-Figure Business After Asking, 'Why Doesn't This Product Exist for Men?'
Entrepreueur Opinions expressed by Entrepreneur contributors are their own. When Jared Pobre and his wife, former WWE star Stacy Keibler, moved to Jackson Hole, Wyoming, he expected more time outdoors, skiing, hiking, fly-fishing. What he experienced was how extreme conditions accelerate skin aging and damage, leaving his skin raw and red. When searching for solutions for his skincare, not only were options limited, but nothing seemed to help.
Entrepreneur Goes from $100M Men's Wear Brand to Smart Baby Monitor Startup
Every good business idea starts with a problem, and Kevin Lavalle had a serious one to solve. Not long after his son was born, he realized the baby monitor app on his phone had crashed. Nothing went wrong, but the realization rattled him. "My son was unmonitored all night," he says. "That is not why parents buy a baby monitor." Realizing the app had failed the one job it had to do, he began researching the market. He discovered there was no device that worked with the internet and without it.
He built a $100 million brand in menswear -- now he's taking on baby monitors after a scary wake-up call
Entrepreueur The opinions expressed by contributors to Entrepreneur are theirs. Kevin Lavalle was faced with a major problem. He realized that the baby monitor application on his phone crashed not long after he had his son. The app was still working, but the crash rattled him.
How a Health Crisis Sparked a $100M a Year Company
When he was 15 years old, Max Clarke would wake up to find blood pouring from his nose. The nosebleeds were relentless, sometimes happening multiple times a week. Doctors couldn't diagnose it. By the time Clarke got to university, he was exhausted and still without answers. So he did something about it. He changed his diet. Started meditating. Practiced yoga. Took supplements. Focused on sleep. "I've never had a nosebleed since," Max Clarke says.
This Former NFL Player Built a Brand Around Nasal Breathing
As a former NFL player and lifelong high performer, Todd Anderson was obsessed with optimization. He'd tried every hack, supplement, and tool he could find. But when he began taking a closer look at sleep, he noticed a glaring gap in the wellness conversation. That shift started when he began working with Dr. Jennifer Martin, a leading sleep researcher at UCLA. After learning he had mild sleep apnea, he began taping his mouth shut at night to encourage nasal breathing.
How One Founder's Lowest Point Launched a Wellness Brand
Chris Mirabile used to wear burnout like a badge of honor. He drank hard, worked crazy hours, and sometimes slept under his desk. "I'd sleep at the office, wake up, and work all day. It was a very unhealthy lifestyle," he says. But Mirabile got a harsh wake-up call when his startup failed. That same year, Hurricane Sandy destroyed his apartment, and thieves robbed him blind. The sudden stroke of bad fortune hit him hard. "I was depressed for about a year," he says.
AI Startup TML From Ex-OpenAI Exec Mira Murati Pays $500,000
The $10 billion AI startup Thinking Machines Lab (TML), which was founded by former OpenAI Chief Technology Officer Mira Murati in February, is paying its technical talent up to half a million dollars in salary, according to federal data obtained by Business Insider. The federal filings, which show how much TML's hires on H-1B visas were being paid, showed that the company paid three technical staffers $450,000 each, while a fourth received $500,000 in compensation.
Why Your Finance Team Needs an AI Strategy, Now
The finance function is evolving fast. Whether it's streamlining close processes or spotting anomalies before they become real problems, artificial intelligence (AI) is no longer just a buzzword. It's a real capability that businesses are expecting finance leaders to adopt. And that expectation extends to the teams they lead. Yet there's one big challenge: most finance departments weren't built for this shift.
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