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Age-related decline in glomerular filtration rate (GFR) is a major driver of chronic kidney disease (CKD) burden, leading to a high prevalence of CKD among older adults [1]. Established risk factors such as hypertension, obesity, and diabetes are well-known contributors to CKD, yet much of the variation in GFR decline remains unexplained [2]. This highlights the need to identify modifiable risk factors and evidence-based lifestyle strategies to prevent CKD.
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