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The occurrence of heavy metal resistance genes in multiresistant Enterobacteriaceae possessing bla or bla genes was examined by PCR and pulsed-field gel electrophoresis with S1 nuclease. Compared with clinical susceptible isolates (10.0% to 30.0%), the pcoA, merA, silC, and arsA genes occurred with higher frequencies in bla -positive (48.8% to 71.8%) and bla -positive (19.4% to 52.8%) isolates, and they were mostly located on plasmids.
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