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Loading metrics Open Access Peer-reviewed Research Article Jozsef Karman , Jing Wang, Corneliu Bodea, Sherry Cao, Marc C. Levesque Jozsef Karman, Jing Wang, Corneliu Bodea, Sherry Cao, Marc C. Levesque Published: March 23, 2021 https://doi.org/10.1371/journal.pone.0248889 Figures Abstract Idiopathic pulmonary fibrosis is a progressive and debilitating lung disease with large unmet medical need and few treatment options.
Open Access Stuart J. Perper, Susan V. Westmoreland, Jozsef Karman, Rachel Twomey, Jane Seagal, Rui Wang, Bradford L. McRae and Stephen H. Clarke J Immunol July 1, 2019, 203 (1) 58-75; DOI: https://doi.org/10.4049/jimmunol.1900043 Key Points CD40 antagonism reverses severe proteinuria and restores glomerular morphology. CD40 antagonism normalizes nephrotic and injury-associated gene expression. CD40 antagonism disrupts multiple disease-critical immunological mechanisms.
Open Access Stuart J. Perper, Susan V. Westmoreland, Jozsef Karman, Rachel Twomey, Jane Seagal, Rui Wang, Bradford L. McRae and Stephen H. Clarke J Immunol May 20, 2019, ji1900043; DOI: https://doi.org/10.4049/jimmunol.1900043 Key Points CD40 antagonism reverses severe proteinuria and restores glomerular morphology. CD40 antagonism normalizes nephrotic and injury-associated gene expression. CD40 antagonism disrupts multiple disease-critical immunological mechanisms.
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