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Abstract Non-tuberculous mycobacterial pulmonary disease (NTM-PD) is an escalating global health concern with poorly defined immunological mechanisms, necessitating comprehensive profiling to guide therapeutic advances. We analyzed peripheral blood from 28 treatment-naïve NTM-PD patients (19 Mycobacterium avium complex, 9 Mycobacterium abscessus) and 27 matched controls using 42-marker mass cytometry (CyTOF) and Luminex multiplex assays.
Preventative administration of IL-27 improves airway inflammation of ovalbumin –induced asthma mice model via both STAT1 and GADD45?/p38MAPK pathways Zhihong Chen, Xiaoqiong Su, Jue Pan, Kan Xu, Xiangdong Wang European Respiratory Journal Sep 2016, 48 (suppl 60) PA1097; DOI: 10.1183/13993003.congress-2016.PA1097
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