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Antiviral Agents Rebekka Adfeldt, Janna Schmitz, Barbara Kropff, Marco Thomas, Natalia Monakhova, Julia E. Hölper, Barbara G. Klupp, Thomas C. Mettenleiter, Vadim Makarov, Elke Bogner DOI: 10.1128/AAC.02103-20 ABSTRACT Herpesviruses are widespread and can cause serious illness. Many currently available antiviral drugs have limited effects, result in rapid development of resistance, and often exhibit dose-dependent toxicity.
Virus-Cell Interactions Sebastian Rönfeldt, Kati Franzke, Julia E. Hölper, Barbara G. Klupp, Thomas C. Mettenleiter Richard M. Longnecker, Editor DOI: 10.1128/JVI.01910-19 ABSTRACT Herpesvirus nucleocapsids leave the nucleus by a vesicle-mediated translocation mediated by the viral nuclear egress complex (NEC). The NEC is composed of two conserved viral proteins, designated pUL34 and pUL31 in the alphaherpesvirus pseudorabies virus (PrV).
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