Author: Julia Squarr, Journal Development Manager, PLOS Pathogens and PLOS Genetics PLOS Genetics finds itself at a juncture marked by both reflection and anticipation. Over the years, the journal has excelled under the leadership of Gregory S. Barsh and Gregory P. Copenhaver, or ‘The Gregs’ as they are affectionately referred to by us all. The journal has been guided by the commitment of The Gregs to uphold the central ethos of PLOS Genetics to be a journal created by and for working scientists.