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JY has received grants from MSD-USA (MISP Call), Pfizer and MEIJI. JY has participated in advisory boards organized by GSK, MSD, and Pfizer. JY declares payments of travel expenses and meeting fees from MSD and Pfizer. JS and MD have participated in advisory boards organized by MSD or Pfizer respectively. CA has received grants from MSD-USA (MISP Call), and Pfizer. CA has participated in advisory boards organized by MSD, and Pfizer. All other authors report no potential conflicts.
Abstract Dynamic trends of invasive pneumococcal disease (IPD) including the evolution of prevalent serotypes are very useful to evaluate the impact of current and future pneumococcal conjugate vaccines (PCVs) and the rise of non-vaccine serotypes. In this study, we include epidemiological patterns of S. pneumoniae before and after COVID-19 pandemic. We characterized all national IPD isolates from children and adults received at the Spanish Pneumococcal Reference Laboratory during 2019-2023.
Research in context Evidence before this study We searched PubMed on Jan 2, 2021 for studies in children and adults published between Jan 1, 2004, and Dec 31, 2020, using the terms “invasive pneumococcal disease” and/or “serotypes”, and “pneumococcal conjugate vaccines”, and “antibiotic resistance”, and “SARS-CoV-2”, with no language restrictions.
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