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Abstract Aging involves complex molecular alterations across tissues. However, a comprehensive understanding of epitranscriptomic dynamics remains elusive.
Abstract Background: Gastric cancer remains a major cause of mortality in China, yet updated nationwide evidence integrating mortality trends, premature mortality burden, and future projections is limited. Using data from China’s Disease Surveillance Points (DSP) system, we evaluated long-term trends in gastric cancer mortality and demographic disparities. Methods: Gastric cancer deaths (ICD-10 code C16) from 2008 to 2021 were obtained from the national DSP system.
1. Introduction Lung cancer is the leading cause of cancer-related death worldwide (1–3). Pulmonary nodules (PNs) are an early and potentially curable form of lung cancer (4). In screening for lung cancer, the average detection rate of PNs has increased to 22.00%−59.70%, of which < 5% are malignant nodules (5–7). Early diagnosis of malignant solid nodules is especially important to improve the prognosis of lung cancer due to its indeterminate aggressive characteristics (8–11).
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