Skip To Main Content
Junju Chen on Muck Rack

Junju Chen

As seen in: Nature, Cell Reports Medicine
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile
Back to Junju Chen’s profile

Articles by Junju Chen

Targeting YRDC blocks codon-biased FABP7 translation and lipid droplet formation to overcome chemoresistance in glioblastoma

|
By Yuchao Zhang, Xuesong Yang, Xixi Li, Chen Zheng, Xuechao Zeng, Junju Chen, Long Cheng, Zhenyan Xu, Yixin Gao, Jian Zhong, Nunu Huang, Xuesong Mike Liu, Kejun He, Nu Zhang, Xujia Wu, Mingpu Gao, Lanjie Chen
| Nature Verified
Abstract Dysregulation of transfer RNA (tRNA) modification and reprogramming of codon-biased translation are commonly associated with cancer initiation and progression. However, their roles in chemoresistance and tumor recurrence remain poorly understood, especially in glioblastoma (GBM). This study establishes the tRNA-modifying enzyme YrdC N6-Threonylcarbamoyltransferase Domain Containing (YRDC) as a key mediator of temozolomide (TMZ) resistance in GBM.
Open in Who Shared Issue with article?

Lnc-H19-derived protein shapes the immunosuppressive microenvironment of glioblastoma

|
By Yixin Gao, Jian Zhong, Xujia Wu, Ming Liu Verified, Yesheng Wang, Yuan Wang, Xuesong Yang, Nunu Huang, Maolei Zhang, Xuesong Mike Liu, Nu Zhang, Junju Chen, Zhaojie Leng, Feizhe Xiao
| Cell Reports Medicine Verified
Keywords GBM TME LncRNA H19 H19-IRP circular RNA vaccine immunotherapy Introduction Glioblastoma (GBM) is the most common and lethal brain tumor in adults.
Open in Who Shared Issue with article?
Show More