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K. Best

As seen in: Color Research & Application, World Allergy Organization Journal, Physiotherapy
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Articles by K. Best

Does utilising a bio-psychosocial environment benefit young people who experience persistent pain?

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By K. Best, L. Dunger
| Physiotherapy Verified
L. Dunger L. Dunger Correspondence Corresponding author. Affiliations Southampton Children's Hospital, University Hospital Southampton, Children's Therapy Department, Southampton, United Kingdom Search for articles by this author K. Best K. Best Affiliations Southampton Children's Hospital, University Hospital Southampton, Children's Therapy Department, Southampton, United Kingdom Search for articles by this author DOI:https://doi.org/10.1016/j.physio.2021.10.181
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Changes in aortic reactivity associated with the loss of equilibrative nucleoside transporter 1 (ENT1) in mice

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By K. Best, Robert Gros, Derek B. Bone, Gonzalo Vilas
| PLOS
Slc29a1 encodes for equilibrative nucleoside transporter subtype 1 (ENT1), the primary mechanism of adenosine transfer across cell membranes. Previous studies showed that tissues isolated from Slc29a1-null mice are relatively resistant to injury caused by vascular ischemia-reperfusion. To determine if there are similar changes in the microvasculature, and investigate underlying mechanism, we examined aortas isolated from wildtype and Slc29a1-null mice.
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Prenatal omega-3 LCPUFA and symptoms of allergic disease and sensitization throughout early childhood - a longitudinal analysis of long-term follow-up of a randomized controlled trial | World Allergy Organization Journal | Full Text

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By K. Best, D. J. Palmer, M. J. Gold
| World Allergy Organization Journal Verified
This longitudinal analysis of our nested allergy cohort from the DOMInO Trial [24] was designed to determine the effect of prenatal ω-3 LCPUFA supplementation on parent reported allergic disease symptoms and sensitization over time. Our results show that a maternal dose of 900 mg of ω-3 LCPUFA per day during pregnancy had no effect on symptoms of allergic disease or sensitization over time.
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Higher infliximab trough levels are associated with perianal fistula healing in patients with Crohn's disease

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By A. Patel, C. Fox, A. J. Yarur, V. Kanagala, D. J. Stein, F. Czul, M. A. Quintero, D. Agrawal, K. Best, K. Idstein, M. T. Abreu
| Color Research & Application Verified
Infliximab has been found to be efficacious in the treatment of fistulas in the setting of Crohn's disease, even though some patients do not benefit from therapy. To assess the correlation between perianal fistula healing and trough levels of infliximab. In this cross-sectional study, we identified patients with Crohn's disease who had perianal fistulas and were treated with infliximab for at least 24 weeks. We excluded patients who underwent a faecal diversion procedure or proctectomy.
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