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Kaelyn Lamberti

As seen in: Nature
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Articles by Kaelyn Lamberti

A phase 2, randomised, placebo-controlled study to evaluate once-daily oral Travelan for the prevention of Travellers’ diarrhoea

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By Joanne Casey, Frederic Poly, Chad K. Porter, Dilara Islam, Renee M Laird, Sandra D. Isidean, Kayla J Testa, Vicky Chapman, Anya E. Shindler, Ashley Franks, Sharon M Tennant, Wilbur H. Chen, Mohamed Al-Ibrahim, Kaelyn Lamberti, Charmagne Beckett, Jerry Kanellos
| Nature Verified
Abstract This study evaluated once-daily oral dosing of Travelan (IMM-124E), a bovine polyclonal antibody product, for prevention of Enterotoxigenic Escherichia coli (ETEC)-induced diarrhoea. In this randomised, double-blind, placebo-controlled trial using an ETEC-controlled human infection model, 60 healthy subjects received 1200mg Travelan or placebo once-daily for 7 days. Two days after dosing commenced, subjects were challenged with ETEC strain H10407 and monitored for diarrhoeal symptoms.
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