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Abstract Introduction: Monitoring children with 21-hydroxylase deficiency (21-OHD) requires suppression of adrenal androgen excess while avoiding glucocorticoid overtreatment. However, the clinical value of serum 11-oxygenated androgens beyond established biomarkers remains uncertain. We evaluated whether serum 11-ketotestosterone (11KT) is associated with overall disease-control status and whether it provides incremental information beyond androstenedione (A4).
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.