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Articles by Kan Zhai
Immunorepertoire-based characterization of adaptive immunity in human malignant pleural effusion
Abstract Background: Malignant pleural effusion (MPE) frequently occurs in patients with advanced cancer and is predominantly infiltrated by lymphocytes, particularly CD4+ T cells. However, the characteristics of adaptive immune cells, including T-cell receptor (TCR) and B-cell receptor (BCR) repertoires, in MPE remain largely unclear.
TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating TH1/TH17 Cell Response
Feng-Shuang Yi, Xin Zhang, Kan Zhai, Zhong-Yin Huang, Xiu-Zhi Wu, Min-Ting Wu, Xin-Yu Shi, Xue-Bin Pei, Shu-Feng Dong, Wen Wang, Yuan Yang, Juan Du, Zeng-Tao Luo and Huan-Zhong Shi J Immunol November 15, 2020, 205 (10) 2926-2935; DOI: https://doi.org/10.4049/jimmunol.2000307 Key Points Myo9b deficiency in tumor cells and host mice both suppress the development of MPE. TSAd expression mediated by Myo9b associates with TH1/TH17 cell differentiation.
TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating TH1/TH17 Cell Response
Feng-Shuang Yi, Xin Zhang, Kan Zhai, Zhong-Yin Huang, Xiu-Zhi Wu, Min-Ting Wu, Xin-Yu Shi, Xue-Bin Pei, Shu-Feng Dong, Wen Wang, Yuan Yang, Juan Du, Zeng-Tao Luo and Huan-Zhong Shi J Immunol October 23, 2020, ji2000307; DOI: https://doi.org/10.4049/jimmunol.2000307 Key Points Myo9b deficiency in tumor cells and host mice both suppress the development of MPE. TSAd expression mediated by Myo9b associates with TH1/TH17 cell differentiation.
TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating TH1/TH17 Cell Response
Feng-Shuang Yi, Xin Zhang, Kan Zhai, Zhong-Yin Huang, Xiu-Zhi Wu, Min-Ting Wu, Xin-Yu Shi, Xue-Bin Pei, Shu-Feng Dong, Wen Wang, Yuan Yang, Juan Du, Zeng-Tao Luo and Huan-Zhong Shi J Immunol October 12, 2020, ji2000307; DOI: https://doi.org/10.4049/jimmunol.2000307 Key Points Myo9b deficiency in tumor cells and host mice both suppress the development of MPE. TSAd expression mediated by Myo9b associates with TH1/TH17 cell differentiation.
IL‐10 promotes malignant pleural effusion by regulating TH1 response via a miR‐7116‐5p/GPR55/ERK pathway in mice
Research Article Kan Zhai Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao‐Yang Hospital, Capital Medical University, Beijing, China These authors contributed equally to this work.
IL‐10 promotes malignant pleural effusion in mice by regulating TH1‐ and TH17‐cell differentiation and migration
The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Research Article IL‐10 promotes malignant pleural effusion in mice by regulating TH1‐ and TH17‐cell differentiation and migration Xiu‐Zhi Wu Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao‐Yang Hospital, Capital Medical University, , Beijing, China These authors contributed equally to this work.
Diagnostic accuracy of interleukin 27 for tuberculous pleural effusion: two prospective studies and one meta-analysis
Methods First, the concentrations of pleural interleukin 27, interferon-gamma and adenosine deaminase were compared between 51 patients with TPE and 103 with non-TPEs (Beijing cohort), and their diagnostic values were evaluated. These were further verified in another independent population (Wuhan cohort, n=120). In the second part of the study, we performed a meta-analysis.
Diagnostic accuracy of interleukin 27 for tuberculous pleural effusion: two prospective studies and one meta-analysis
Methods First, the concentrations of pleural interleukin 27, interferon-gamma and adenosine deaminase were compared between 51 patients with TPE and 103 with non-TPEs (Beijing cohort), and their diagnostic values were evaluated. These were further verified in another independent population (Wuhan cohort, n=120). In the second part of the study, we performed a meta-analysis.
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