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1 INTRODUCTION Sepsis is a life-threatening multiorgan dysfunction caused by the host's innate immune response to bacterial, fungal, or viral infection.1 Acute lung injury (ALI) may arise during the early stages of sepsis. The etiology of ALI is intricate, and up-to-date findings have indicated that inflammation is a crucial mechanism in its onset.
1 INTRODUCTION Severe infection refers to a state where a disease or pathogen rapidly multiplies and spreads within the human body, leading to severe symptoms and posing a threat to life.1 Severe infections can result in organ failure, shock, respiratory failure, and other serious complications. It is a common and critical condition with relatively high incidence and mortality rates worldwide,2 necessitating prompt treatment for life-saving intervention.
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