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Rapid growth and development during childhood and adolescence pose challenges to paediatric healthcare, including blood test interpretation.1 Physicians may order blood tests in children and adolescents with signs and symptoms suggestive of a health condition. Blood tests can be used for screening, risk assessment, disease diagnosis or prognosis, and treatment initiation or monitoring (box 1).
AbstractA healthy skeletal muscle mass is essential in attenuating the complications of obesity. Importantly, healthy muscle function is maintained through adequate repair following overuse and injury. The purpose of this study was to investigate the impact of diet?induced obesity (DIO) on skeletal muscle repair and the functionality of the muscle satellite cell (SC) population. Male C57BL/6J mice were fed a standard chow or high?fat diet (60% kcal fat; DIO) for 8 weeks.
AbstractShort?term consumption of a high?fat diet (HFD) can result in an oxidative shift in adult skeletal muscle. However, the impact of HFD on young, growing muscle is largely unknown. Thus, 4?week?old mice were randomly divided into sedentary HFD (60% kcal from fat), sedentary standard chow (control), or exercise?trained standard chow. Tibialis anterior (TA) and soleus muscles were examined for morphological and functional changes after 3 weeks.
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