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Articles by Katherine Chaplin
Patient outcome following selective serotonin reuptake inhibitor prescribing in primary care in Wales (UK)
1 INTRODUCTION Antidepressant prescribing has increased over the past two decades both in the United Kingdom (Bogowicz et al., 2021; Hafferty et al., 2019; Lockhart & Guthrie, 2011) and elsewhere (Forns et al., 2019; Lipovec et al., 2022).
Antidepressant prescribing patterns and adverse events following introduction of a National Prescribing Indicator to monitor dosulepin usage in Wales
Abstract Aim Limiting use of the antidepressant dosulepin has been encouraged due to associated risks of toxicity. In April 2011 the All Wales Medicines Strategy Group introduced a National Prescribing Indicator (NPI) to monitor dosulepin usage. The aim of this study was to investigate antidepressant prescribing patterns, and selected adverse events in patients prescribed dosulepin following introduction of the NPI. Methods An e-cohort study was conducted.
Cost-effectiveness of a patient-centred approach to managing multimorbidity in primary care: a pragmatic cluster randomised controlled trial
Cost-effectiveness of a patient-centred approach to managing multimorbidity in primary care: a pragmatic cluster randomised controlled trial Joanna Thorn1, Mei-See Man1,2, Katherine Chaplin1, Peter Bower3, Sara Brookes2, Daisy Gaunt2, Bridie Fitzpatrick4, Caroline Gardner3, Bruce Guthrie5, Sandra Hollinghurst1, Victoria Lee3, Stewart W Mercer4, Chris Salisbury1 1Centre for Academic Primary Care, Bristol Medical School, University of Bristol, Bristol, UK 2Bristol Randomised Trials...
Development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ)
In order to understand the impact of treatment burden, and particularly to assess the effects of interventions that might increase or decrease burden, a valid patient-reported outcome measure (PROM) is essential. There are four existing PROMs that measure aspects of treatment burden for patients with multimorbidity, 4–8 all of which have important limitations.
Association of BCG, DTP, and measles containing vaccines with childhood mortality: systematic review
Conclusions Evidence suggests that receipt of BCG and MCV reduce overall mortality by more than would be expected through their effects on the diseases they prevent, and receipt of DTP may be associated with an increase in all cause mortality. Although efforts should be made to ensure that all children are immunised on schedule with BCG, DTP, and MCV, randomised trials are needed to compare the effects of different sequences. Results Results from 34 birth cohorts were identified.
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