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Introduction Click to copy section linkSection link copied! Antibody drug conjugates (ADCs) are a proven approach to targeted cancer therapy. (1) These unique drugs capitalize on the selectivity of a monoclonal antibody (mAb) to deliver a cytotoxic payload to cancer cells by connecting the payload to the mAb through an enzyme-cleavable linker. Over the past decade, 12 unique ADCs have been brought to the market for various therapies.
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