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Articles by Kay Nguo
A Retrospective Cohort Study of Nutrition Outcomes in Children With Spinal Muscular Atrophy Type 1 and 2 Treated With Disease Modifying Therapies
DMTs disease modifying therapies DXA dual-energy X-ray absorptiometry GI gastrointestinal IQR interquartile range NIV non-invasive ventilation OA onasemnogene abeparvovec PPI proton-pump inhibitor SMA spinal muscular atrophy SMN survival motor neuron 1 Introduction In the last decade, three disease modifying therapies (DMTs) (nusinersen, risdiplam and onasemnogene abeparvovec) were approved for the treatment of spinal muscular atrophy (SMA) by the United States Food and Drug Administration...
Nutrition outcomes of disease modifying therapies in spinal muscular atrophy: A systematic review
BMI body mass index DMT disease modifying therapy EMA European Medicines Agency FDA Food and Drug Administration GI gastrointestinal PICO population, intervention, comparator and outcomes PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses REE resting energy expenditure SMA spinal muscular atrophy SMN survival motor neuron 1 INTRODUCTION Spinal muscular atrophy (SMA) is a degenerative neuromuscular disorder characterized by progressive muscle weakness and atrophy.
Effect of macronutrient composition on meal-induced thermogenesis in adolescents with obesity
European Journal of Nutrition September 2019, Volume 58, Issue 6, pp 2327–2333 | Cite as Original Contribution First Online: 20 July 2018 Shares 214 Downloads Abstract Purpose Manipulation of meal macronutrient may be a useful way to modulate meal-induced thermogenesis (MIT) to induce increases in energy expenditure. The objective of this study was to examine in adolescents with obesity and of healthy weight and the effect of a high protein and high carbohydrate meal on MIT.
Total energy expenditure in adults aged 65 years and over measured using doubly-labelled water: international data availability and opportunities for data sharing | Nutrition Journal | Full Text
Our database search identified no reviews that had undertaken a systematic approach to identifying and collating the literature reporting TEE measured using DLW in an elderly population. Following the process of searching the literature, extracting data where reported, or contacting research teams of published studies, we identified 890 participant-level data points of TEE from individuals aged 65 years and over.
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