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Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major economic threat to the global swine industry. The viral 3C-like serine main protease (non-structural protein 4, nsp4) is essential for replication and represents a promising drug target for antiviral intervention.
Abstract Background: Coronary artery calcification is a key predictor of cardiovascular disease. However, the association between serum uric acid and incident coronary artery calcification remains controversial, and relevant evidence from Chinese populations is limited. Methods: We conducted a retrospective cohort study including 6,996 participants without coronary artery calcification at baseline, as detected by low-dose chest computed tomography.
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