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Articles by Keyan Chen
Fruquintinib plus sintilimab in advanced cervical cancer: an open-label, multicentre, phase 2 study
Abstract Efficacy of second-line treatments after first-line platinum-based chemotherapy in advanced cervical cancer is modest. This open-label, single-arm, multicentre, proof-of-concept phase 2 study evaluated fruquintinib plus sintilimab in advanced cervical cancer. Patients recruited between July 2021 and June 2022 had received at least first-line platinum-based chemotherapy or were unable to receive standard treatment in China.
Predicting the risk of chemotherapy-induced myelosuppression in clinical practice: an interpretable machine learning approach based on routine laboratory data
Abstract Objective: Chemotherapy-induced myelosuppression (CIM) is the most common adverse reaction of tumor chemotherapy and may lead to treatment delay, dose reduction, life-threatening infection, and poor prognosis. Current predictive methods remain suboptimal, with insufficient interpretability and limited clinical application. This study aimed to develop and validate an interpretable machine learning model for early CIM risk prediction using routine laboratory data.
Exploring the Relationship between Key Perceptual Elements of Urban Secondary Wilderness and Its Restorative Benefits
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Effect of Al Substitution on Visible Short-Wave Infrared Reflectance Spectroscopy (VSWIR) of Goethite and Ferrihydrite
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Multiple time servers timed-release encryption based on Shamir secret sharing for EHR cloud system - Journal of Cloud Computing
The design goal of the proposed schemes is that the receiver can decrypt the ciphertext C normally at the decryption time specified by the sender. In this section, we introduce a common time server management organization to the system and further present our TRE system model based on Shamir secret sharing, as shown in Fig. 1. The system consists of five entities: the time server management organization, N time servers, the private key generator, the data sender, and the data receiver.
Timed-release encryption anonymous interaction protocol based on smart contract - Journal of Cloud Computing
This section will present the TAISC protocol model and briefly describe the involved participants, the objective, workflow, and potential attacks. The TAISC protocol involves three participating entities: a sender, a middleman cluster, and a time server. Middleman refers to the blockchain peer(node) that provides services and registers to the contract. Sender(Bob). Bob is the data recipient in the TRE protocol but is referred to as the sender in the following text for ease of exposition.
Dual‐branch feature extraction network combined with Transformer and CNN for polyp segmentation
CONFLICT OF INTEREST STATEMENT The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this article. The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Qiaohong Liu reports financial support was provided by National Natural Science Foundation of China. REFERENCES 1, , , . Cancer statistics, 2021. CA Cancer J Clin.
Prioritizing Organic Pollutants for Shale Gas Exploitation: Life Cycle Environmental Risk Assessments in China and the US
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Smartphone-Enabled Fluorescence and Colorimetric Platform for the On-Site Detection of Hg2+ and Cl− Based on the Au/Cu/Ti3C2 Nanosheets
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Facile Synthesis of MXene-Ti3C2/Co Nanosheet Hydrogel Sensor with the Assistance of a Smartphone for On-Site Monitoring of Glucose in Beverages
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