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Articles by Khalil Mallah
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury - Signal Transduction and Targeted Therapy
Abstract Repeated mild closed head injury (rmCHI) is a significant public health concern, and this type of repetitive injury is garnering increasing attention, not least because of its increasing incidence in sports. The underlying neuroimmune mechanisms secondary to trauma that link rmCHI to cognitive impairment remain to be elucidated, and the contribution of the complement system to the pathological sequelae of this type of brain injury is unexplored.
Uncovering injury-specific proteomic signatures and neurodegenerative risks in single and repetitive traumatic brain injury - Signal Transduction and Targeted Therapy
Abstract Traumatic brain injury (TBI) is a major public health concern associated with an increased risk of neurodegenerative diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD), and chronic traumatic encephalopathy, yet the underlying molecular mechanisms in repetitive TBI remain poorly defined.
Complement Drives Chronic Inflammation and Progressive Hydrocephalus in Murine Neonatal Germinal Matrix Hemorrhage
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Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Lipids in Experimental Model of Traumatic Brain Injury Detecting Acylcarnitines as Injury Related Markers
Identifying new lipid markers linked to traumatic brain injury (TBI) is of major importance in characterizing their central role in the regeneration process and inflammatory response in such an injury model.
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