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1 INTRODUCTION Growth factor receptor-bound 7 (Grb7) is a member of the Grb7/Grb10/Grb14 family of adapter proteins. The human (532 amino acid) and mouse (535 amino acid) Grb7 proteins have the same multidomain structure and are 93% homologous. Grb7 consists of several domains facilitating protein–protein interactions and lacks enzymatic activity.
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