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L. K. Ward

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Articles by L. K. Ward

Vancomycin relieves mycophenolate mofetil-induced gastrointestinal toxicity by eliminating gut bacterial β-glucuronidase activity

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By T. Louie, B. Byrne, J. D. Emery, L. K. Ward
| Science Magazine Verified
Abstract Mycophenolate mofetil (MMF) is commonly prescribed and has proven advantages over other immunosuppressive drugs. However, frequent gastrointestinal side effects through an unknown mechanism limit its use. We have found that consumption of MMF alters the composition of the gut microbiota, selecting for bacteria expressing the enzyme β-glucuronidase (GUS) and leading to an up-regulation of GUS activity in the gut of mice and symptomatic humans.
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Our Favorite Water Pokémon and Their Real-Life Doppelgängers

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By L. K. Ward
| Smithsonian
Pokémon Go came out in the United States last week and it’s safe to say that the gaming community is collectively losing its mind. Already boasting an estimated 7.5 million downloads as of Monday, 6 days after the release, the Nintendo-owned franchise is making a raging comeback. The game uses your smartphone’s GPS to locate virtual Pokémon in your vicinity allowing the player to both see and “capture” Pokémon à la augmented reality through your phone’s camera. Still confused?
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Unearthing History: Mary Anning's Hunt for Prehistoric Ocean Giants

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By L. K. Ward
| Smithsonian
You may not have realized it, but you’ve been acquainted with Mary Anning since you were young. Remember this grade school tongue-twister? What you probably didn’t know is that this nursery rhyme is based on a real person who not only sold seaside curiosities by the seashore, but became world renowned for her fossil discoveries. Caption: Portrait of Mary Anning, before 1842. Oil painting by unknown artist. Courtesy of The Trustees of the Natural History Museum, London.
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