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L. Scotto

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Articles by L. Scotto

Identifying the mechanistic differences between hypomethylating agents for the treatment of peripheral T cell lymphoma

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By L. Scotto, I. Pal, A. Sabzevari, C. Kinahan
| Wiley Online Library Verified
Introduction: Peripheral T-cell lymphomas (PTCL) are a rare and heterogeneous group of malignancies that share a unifying feature of epigenetic dysregulation. Recent evidence suggests that PTCL, unlike other forms of cancer or even lymphoma, exhibits a marked vulnerability to hypomethylating agents (HMAs) alone and especially in combination with HDAC inhibitors. HMAs like azacitidine (AZA) and decitabine (DAC) have been shown to reverse transcriptional repression secondary to hypermethylation.
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A Next-Generation Liquid Xenon Observatory for Dark Matter and Neutrino Physics

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By D. Antón, T. Marrodán, A. Cimental, L. Scotto
| cds.cern.ch
Author(s) Aalbers, J. (SLAC ; KIPAC, Menlo Park) ; Abe, K. (Kamioka Observ. ; Tokyo U., IPMU) ; Aerne, V. (Zurich U.) ; Agostini, F. (U. Bologna, DIFA ; INFN, Bologna) ; Maouloud, S. Ahmed (Paris U., VI-VII) ; Akerib, D.S. (SLAC ; KIPAC, Menlo Park) ; Akimov, D.Yu. (Moscow Phys. Eng. Inst.) ; Akshat, J. (Purdue U.) ; Musalhi, A.K. Al (Oxford U.) ; Alder, F. (University Coll. London) ; Alsum, S.K. (Wisconsin U., Madison) ; Althueser, L.
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