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Articles by L. Ylitalo
DL‐PDT for AK: multicentre trial comparing BF‐200 ALA with MAL
Summary Actinic keratoses (AK) are areas of sun‐damaged skin found mainly on parts of the body which have received lots of sun exposure. At first, they can be hard to see, and are more easily felt, being rough, like sandpaper. They may grow to a centimetre or two in diameter. Up to 20% of AKs may progress to a type of skin cancer called squamous cell carcinoma (SCC) within 10 to 25 years.
光化性角化病日光光动力疗法:对比 BF‐200 ALA 与 MAL 的多中心试验
Plain Language Summary 光化性角化病日光光动力疗法:对比 BF‐200 ALA 与 MAL 的多中心试验 British Journal of Dermatology, 181, 265–274, August 2019 PDF PDF Share Summary 光化性角化病(AK)是被阳光晒伤的皮肤区域,多见于受到阳光暴晒的身体部位。起初很难看到病灶,但能够感觉到皮肤变硬,就像砂纸一样。病灶直径可能增至1~2厘米。高达20%的AK可能会在10~25年内发展成一种名为鳞状细胞癌(SCC)的皮肤癌。该病症的一种治疗方法为日光光动力疗法(DL‐PDT),需要在病灶(受影响的皮肤区域)上涂敷含有“感光剂”的乳膏。感光剂本身是非活性的。但是当特定波长的光线照射在涂有感光剂的皮肤上时,感光剂会被激活,这种治疗可杀灭皮肤中的异常细胞。本研究的目的在于对比两种感光剂BF‐200...
5‐aminolevulinic acid nanoemulsion (BF‐200 ALA) is more effective than methyl‐5‐aminolevulinate (MAL) in daylight photodynamic therapy for actinic keratosis: A non‐sponsored randomized double‐blind multicentre trial - Räsänen - - British Journal of Dermat
This non‐sponsored, prospective randomized double‐blind multicentre trial included 69 patients with 767 grade I‐II AKs located symmetrically on the face or scalp. A single DL‐PDT was given in a randomized split‐face design. The primary outcome was clearance of the AKs at 12 months as assessed by a blinded observer. The secondary outcomes were pain, treatment reactions, cosmetic outcome and the cost‐effectiveness of the therapy.
5‐aminolaevulinic acid nanoemulsion is more effective than methyl‐5‐aminolaevulinate in daylight photodynamic therapy for actinic keratosis: a nonsponsored randomized double‐blind multicentre trial - Räsänen - 2019 - British Journal of Dermatology - Wiley
Clinical Trial 5‐aminolaevulinic acid nanoemulsion is more effective than methyl‐5‐aminolaevulinate in daylight photodynamic therapy for actinic keratosis: a nonsponsored randomized double‐blind multicentre trial† J.E. Räsänen Corresponding Author E-mail address: janne.rasanen@sll.fimnet.fi http://orcid.org/0000-0003-3809-384X Department of Dermatology, Joint Authority for Päijät‐Häme Health and Wellbeing, Lahti, Finland Department of Dermatology, Faculty of Medicine and Life Sciences,...
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