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Abstract Donor cell leukemia is a rare but severe complication following an allogeneic hematopoietic stem cell transplantation (allo-HSCT), particularly in patients with non-malignant diseases, due to its aggressive clinical progression and poor prognosis. In recent years, with the increasing number of umbilical cord blood stem cell transplantation cases, umbilical cord blood–derived donor cell leukemia has garnered growing attention.
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