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Articles by Lang Nan
Droplet-based single-cell pairing for high-throughput interaction mapping of antigen-receptor combinations
Abstract Mapping the interaction potential of different variant combinations of viral antigens and human cell receptors and understanding how viral antigen mutations interact with human genetic polymorphisms are critical for predicting infection susceptibility and informing precision public health strategies.
Single‐Target Pairing System (StarPair) for Large‐Scale Interrogation of Cell-Cell Interactions
1 Introduction Cells are indispensable for maintaining the structures and functions of complex multicellular organisms.
Author Correction: High-throughput screening of genetic and cellular drivers of syncytium formation induced by the spike protein of SARS-CoV-2 - Nature Biomedical Engineering
Correction to: Nature Biomedical Engineering https://doi.org/10.1038/s41551-023-01140-z, published online 23 November 2023. In the version of this article initially published, the name of Ho Cheung Shum was shown incorrectly (as Anderson H. C. Shum) and has been amended in the HTML and PDF versions of the article.
Development and future of droplet microfluidics
Development and future of droplet microfluidics Over the past two decades, advances in droplet-based microfluidics have facilitated new approaches to process and analyze samples with unprecedented levels of precision and throughput. A wide variety of applications has been inspired across multiple disciplines ranging from materials science to biology. Understanding the dynamics of droplets enables optimization of microfluidic operations and design of new techniques tailored to emerging demands.
High-throughput screening of genetic and cellular drivers of syncytium formation induced by the spike protein of SARS-CoV-2 - Nature Biomedical Engineering
Abstract Mapping mutations and discovering cellular determinants that cause the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to induce infected cells to form syncytia would facilitate the development of strategies for blocking the formation of such cell–cell fusion.
Functions and applications of artificial intelligence in droplet microfluidics
Functions and applications of artificial intelligence in droplet microfluidics Huan Liu,†a Lang Nan,†b Feng Chen, a Yue Zhaoa and Yongxi Zhao *a Abstract Droplet microfluidics has emerged as a powerful technology to perform high-throughput experiments, while artificial intelligence (AI) serves as a functional tool to analyze a large set of multiplex data.
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