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Abstract Acute kidney injury (AKI) is associated with increased morbidity and mortality and may develop secondary to systemic inflammatory conditions. Conventional biomarkers, such as serum creatinine and urinary gamma-glutamyl transferase (GGT), often fail to detect early renal injury.
Hemangiosarcoma is a rapidly growing and aggressive malignant neoplasm, demonstrating significant metastatic potential due to its vascular association [1]. In dogs, the primary site of development is typically the spleen, followed by other locations such as subcutaneous tissue, dermis, liver, and right atrium [2,3,4,5]. Less common sites include the retroperitoneum, reproductive system, lung, and urinary system [6,7,8,9].
Em 1960, Clarice Lispector e Carolina Maria de Jesus —escritoras que já tinham então seus livros publicados pela mesma editora— posaram para uma foto histórica. Décadas depois, Benjamin Moser, biógrafo de Clarice, usou o retrato e descreveu Carolina como "negra que escreve" e que parecia a "empregada doméstica de Clarice".
This review provides evidence of an association between somatic comorbidities and multifaceted LOAD progression. Given that time-varying comorbidity burden, but much less so baseline comorbidity burden, was associated with the three dimensions prospectively, this relationship cannot be reduced to a simple cause-effect relation and is more likely to be dynamic.
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