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Articles by Lars Libuda
Exploring serum biomarkers in paediatric psychiatry: the impact of NfL and GFAP
Abstract Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (GFAP) are biomarkers of neuroaxonal and astrocytic damage but remain understudied in adolescent psychiatric populations. This study investigated sNfL and GFAP levels in 412 adolescents diagnosed with anorexia nervosa (AN) (n = 52), depression (n = 237), and other psychiatric disorders (n = 123). We assessed their diagnostic utility, correlation with disease severity, and longitudinal changes during AN treatment.
Full Breastfeeding and Allergic Diseases-Long-Term Protection or Rebound Effects?
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A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder
Abstract Background While observational studies revealed an inverse association between serum 25(OH)vitamin D (25(OH)D) and the risk of attention deficit/hyperactivity disorder (ADHD), the causality of this relationship remains unclear. Methods We conducted a bidirectional two-sample Mendelian Randomization (MR) study to examine whether 25(OH)D has an effect on the risk to develop ADHD or vice versa.
Long‐term effects of hydrolyzed formulae on atopic diseases in the GINI study
LETTER TO THE EDITOR Monika Gappa, Department of Pediatrics, Research Institute, Marien-Hospital Wesel, Wesel, Germany Evangelisches Krankenhaus Düsseldorf, Children‘s Hospital, Düsseldorf, Germany Search for more papers by this author Birgit Filipiak-Pittroff, orcid.org/0000-0002-1498-8676 Department of Pediatrics, Research Institute, Marien-Hospital Wesel, Wesel, Germany Search for more papers by this author Lars Libuda, Department of Pediatrics, Research Institute, Marien-Hospital Wesel,...
Effect of vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients: results of a randomized controlled trial
Abstract Purpose While observational studies revealed inverse associations between serum vitamin D levels [25(OH)D] and depression, randomized controlled trials (RCT) in children and adolescents are lacking. This RCT examined the effect of an untreated vitamin D deficiency compared to an immediate vitamin D3 supplementation on depression scores in children and adolescents during standard day and in-patient psychiatric treatment.
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