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Detailed kinetic data of the interaction of human, cynomolgus monkey, bovine, rat and mouse FcRn with IgG isotypes from different species are available [11, 15, 34–37], however, to date no data has been reported concerning the kinetics of the rbFcRn interaction with rbIgG and hIgG isotypes. FcRn experts apply two different SPR experimental set-ups, either FcRn or IgG molecules are immobilized on the sensor chip surface.
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