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Articles by Laura Goracci
A lipidomics roadmap: from basic research to societal challenges
Abstract Lipidomics, a rapidly evolving discipline at the interface of biology and analytical chemistry, seeks to comprehensively characterize the lipid composition of biological systems. Driven by advances in mass spectrometry, chromatography and computational analysis, lipidomics has enabled the high-resolution mapping of lipid networks and their functional dynamics across molecular, cellular and organismal scales.
A lipidomic approach towards identifying the effects of fragrance hydroperoxides on keratinocytes
ACD allergic contact dermatitis BC benzalkonium chloride Chol cholesterol CE cholesterol esters Cer ceramides DG diacylglycerols DNFB 2,4-dinitrofluorobenzene FA fatty acids GlcCer glucosylceramides GPL glycerophospholipids HexnCer hexosylceramide KCs keratinocytes LLNA local lymph node assay PC phosphatidylcholines PC O- alkyl-acyl phosphatidylcholines PE O- alkyl-acyl phosphatidylethanolamines PI phosphatidylinositols PL phospholipids ROS reactive oxygen species SL sphingolipids SM...
Wireless over‐ear headphones: A new source of allergic contact dermatitis to isothiazolinones
Corresponding Author Luca Stingeni Dermatology Section, Department of Medicine and Surgery, University of Perugia, Italy Correspondence Luca Stingeni, Dermatology Section, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy. Email: luca.stingeni@unipg.it Contribution: Conceptualization, Investigation, Writing - review & editing, Writing - original draft Search for more papers by this author
Discovery and Structure-Activity Relationshsips of Novel ssDAF-12 Receptor Modulators
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Med. Chem. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Discovery and Structure-Activity Relationshsips of Novel ssDAF-12 Receptor Modulators
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Med. Chem. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
MARS: A Multipurpose Software for Untargeted LC-MS-Based Metabolomics and Exposomics
Download Hi-Res ImageDownload to MS-PowerPointCite This:Anal. Chem. 2024, XXXX, XXX * , , , , , , , , , and Gabriele Cruciani Department of Chemistry, Biology and Biotechnology, Universita degli Studi di Perugia, via Elce di Sotto 8, Perugia 06123, Italy Cite this: Anal. Chem. 2024, XXXX, XXX .
MARS: A Multipurpose Software for Untargeted LC-MS-Based Metabolomics and Exposomics
Download Hi-Res ImageDownload to MS-PowerPointCite This:Anal. Chem. 2024, XXXX, XXX RETURN TO ARTICLES ASAPPREVArticleNEXT * , , , , , , , , , and Gabriele Cruciani Department of Chemistry, Biology and Biotechnology, Universita degli Studi di Perugia, via Elce di Sotto 8, Perugia 06123, Italy Cite this: Anal. Chem. 2024, XXXX, XXX .
Proteolysis targeting chimeras in antiviral research
Targeted protein degradation (TPD) technology clearly represents a hot topic in drug design that is emerging as a new, exciting approach to the removal of disease-related protein targets from cells [1,2]. Indeed, proteolysis targeting chimeras (PROTACs) are hetero-bifunctional molecules with one end binding to a protein of interest (POI) and the other end, joined by a linker, hijacking an E3 ligase, thus leading to the formation of POI–PROTAC–E3 ternary complexes.
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