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As seen in: Frontiers
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Articles by Le Feber

Impact of background input on memory consolidation in In-Vitro neural networks

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By Van Putten, Le Feber, Michel J.A.M
| zenodo.org
Memory consolidation is a complex process, that can be divided into two stages: first, memories are temporary stored in hippocampus and in the second stage, repeated replay slowly transfers memories to the neo-cortex for long-term consolidation. This 2nd stage occurs during slow wave sleep, a phase characterized in the cortex by low cholinergic tone and low afferent input.
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Investigating the reliability of the evoked response in human iPSCs-derived neuronal networks coupled to micro-electrode arrays

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By van Gestel, van Rhijn, Le Feber, Van Der Raadt
| American Institute of Physics
Topics MATLAB, Electrodes, Bioengineering, Diseases and conditions, Astrocyte, Bioelectronics, Mammals, Cell cultures, Statistical analysis The brain stands as our body's ultimate enigma, with neuron interactions holding mysteries yet unraveled. While acquiring electrophysiological data in vivo remains challenging, in vitro neuronal networks present themselves as formidable assets, helping to shed light on the brain's intricate workings.
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Selective recording of physiologically evoked neural activity in a mixed autonomic nerve using a minimally invasive array

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By Van Asselt, van Mastrigt, Le Feber, Dos Santos Nielsen
| American Institute of Physics
Peripheral nerves projecting to visceral organs are a major therapeutic target for closed-loop devices (Cracchiolo , 2021). These nerves are a major brain–body interface, transmitting both sensory (afferent) signals that monitor the physiological and pathophysiological state of the body, and the motor (efferent) signals that directly control visceral organ function during state-dependent feedback (homeostasis) or feedforward (allostasis) brain regulation (Schulkin and Sterling, 2019).
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Oxygen Gradient Generator to Improve in Vitro Modeling of Ischemic Stroke

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By Le Feber
| Frontiers
João Santiago1, Joose Kreutzer2, Elsbeth Bossink1, Pasi Kallio2 and Joost Le Feber1* 1University of Twente, Netherlands 2Tampere University, Finland The final, formatted version of the article will be published soon. You just subscribed to receive the final version of the article In the core of a brain infarct, perfusion is severely impeded, and neuronal death occurs within minutes.
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